104 Within a few hours, inebriation is followed by nausea, vomiting, ataxia, nystagmus, ophthalmoparesis, myoclonus, seizures, delirium, hallucinations, and stupor or coma. It is poisonous if swallowed. Ethylene glycol has a sweet taste, is colourless and poisoning is more frequent than methanol intoxication. Ethylene glycol (EG) is a common constituent of anti-freeze, coolants and other solvents and is responsible for both inadvertent and intentional poisoning. Poisoning induced by alcohols requires rapid recognition and early treatment as they can cause neurological changes, acute kidney injury and death. Most intoxications are associated with ingestion of antifreeze, which is typically 95% EG. Ethylene glycol is a colorless, odorless, sweet-tasting chemical. Introduction. 1 Ethylene glycol poisoning may pose diagnostic difficulties if the history of ingestion is not volunteered, or if the presentation is delayed.
Ethylene glycol, best known as a component of antifreeze, has been ingested both deliberately and accidentally, resulting in neurotoxicity and renal failure. Present in antifreeze and brake fluids, ethylene glycol is deliberately drunk as an ethanol substitute, and several thousand cases of ethylene glycol poisoning are reported yearly in the United States. Ethylene glycol toxicity is a type of toxic leukoencephalopathy. Ethylene glycol may be swallowed accidentally, or it may be taken deliberately in a suicide attempt or as a substitute for drinking alcohol (ethanol). All animals are susceptible to ethylene glycol (EG) toxicity, but it is most common in dogs and cats. These 95% commercial antifreeze preparations are diluted ~50% with water when used in vehicle cooling systems. Ethylene glycol poisoning.
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